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CySeq® technology

Cyclomics has developed a revolutionary DNA preparation technology which brings unprecedented accuracy to long-read sequencing. By transforming how mutations are detected, our technology eliminates sequencing errors to deliver clarity when it matters most. 

CySeq® in a nutshell

CySeq circularizes each DNA molecule and copies it head-to-tail by rolling circle amplification, then reads every tandem copy and calls a consensus allowing ultra-low frequency mutation detection with confidence.

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Resources

Genome Research

Nanopore-based consensus sequencing enables accurate multimodal tumor cell-free DNA profiling

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npj Genomic Medicine

Accurate detection of circulating tumor DNA using nanopore consensus sequencing

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